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CONTACT: Plzenska 130/221, Prague 5 - Motol, Czech Republic

tel.:      +420 251619629, +420 604242593

e-mail:   novotny@essenceline.cz
A C T I V I T I E S

ANALYTICAL SERVICES

RESEARCH AND BIOINFORMATICS

  • Development of new Analytical and Screeenig Methods
  • Research of new Potential Diagnostic Markers

MEDICAL APPLICATIONS

  • Neonatal Diagnostics
  • Cancer Diagnostics
  • Metabolomics
CNS PHARMACOGENETICS AND PHARMACOKINETICS
  • Pharmacogenetics using microarrays
  • Microdialysis in rodents using certified GMO animal facility

  • Quantitative analysis of CNS biomarkers (LC-MS/MS, LC-MS QTOF, LC-UV, LC-ECD, NMR, qPCR, microarray)

  • Routine HPLC-MS/MS analysis of neurotransmitters (dopamine, DOPAC, HVA, 3-MT, serotonin, 5-HIAA, norepinephrine, GABA, glutamate from microdialysis sample or brain tissue) and ROS biomarkers (leukotriens, prostaglandins, aldehydes)

MICROARRAY QUALITY INSPECTION
  • Spot quality inspection using AFM
  • Homogeneity
  • Complete/partial spot absence
  • DNA aggregation and "donut-shaping"
  • morphological organization on nano-level
  • deposition of biomolecules (clustering, accretion, pooling)
  • co-funded by EUREKA, European funding and support programme for SME research and development
ANIMAL CARE - SCREENING OF TOXINS
  • Elementary Analysis using XRF
  • Screening of Plant toxins using HPLC-MS and NMR
  • Complete toxin fingerprint including the most common equine toxic plants (Ragweed, Yew, Ranunculi, Tansy, Monkshood, Dwale, HerbParis (Paris quadrifoliaL.))
   

SUPPLIES OF CHEMICALS
Fine chemicals, Intermediates
  • Original Technology Development
  • Scale Up
  • Industrial Supplies