ESSENCE
LINE
provides full microdialysis service in rodents. Combination
of microdialysis technique and mass spectroscopy allow us to monitor
chemistry changes
in extracellular environment of living tissue. We can monitor the levels of
drugs and their metabolites as well as the levels of endogenous compounds in
freely moving animals. Just tell us WHAT biomarkers or drugs you
want to analyze and in WHICH area of brain !
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Microdialysis
- Microdialysis
probe implementation
-
Pharmacokinetics and drug brain delivery
-
Routine analysis of neurotransmitters and their metabolites (dopamine,
DOPAC, HVA, 3-MT, serotonin, 5-HIAA, NA, GABA and glutamate) in pM range
from microdialysis samples.
- Custom method development and validation upon
request.
RT-PCR & microarrays
HPLC-MS/MS, NMR
Schizophrenia, Parkinson,
Alzheimer, Custom
