ANALYTICAL SERVICES

ESSENCE LINE provides complete bionalytical services essential for monitoring human and animal biomarkers, biomarker discovery and drug development. In cooperation with academic institutes, we develop original analytical methods and apply them in practise using HPLC-MS/MS, NMR, RT-PCR and microarrays.

• Development of new Analytical and Screeening Methods applicable in clinical practise
• Screening of new Potential Diagnostic Markers
• Routine biomarker monitoring

  MEDICAL APPLICATIONS

• Prenatal Diagnostics
• Cancer Diagnostics
• Metabolomics

  CNS PHARMACOGENETICS AND PHARMACOKINETICS

• Pharmacogenetics using microarrays
• Microdialysis in rodents using certified GMO animal facility

• Quantitative analysis of CNS biomarkers (LC-MS/MS, LC-MS QTOF, LC-UV, LC-ECD, NMR, qPCR, microarray)

• Routine HPLC-MS/MS analysis of neurotransmitters (dopamine, DOPAC, HVA, 3-MT, serotonin, 5-HIAA, norepinephrine, GABA, glutamate from microdialysis sample or brain tissue) and ROS biomarkers (leukotriens, prostaglandins, aldehydes)

  MICROARRAY QUALITY INSPECTION

• Spot quality inspection using AFM
• Homogeneity
• Complete/partial spot absence
• DNA aggregation and "donut-shaping"
• morphological organization on nano-level
• deposition of biomolecules (clustering, accretion, pooling)
• co-funded by EUREKA, European funding and support programme for SME research and development

  ANIMAL CARE - SCREENING OF TOXINS

• Elementary Analysis using XRF
• Screening of Plant toxins using HPLC-MS and NMR
• Complete toxin fingerprint including the most common equine toxic plants (Ragweed, Yew, Ranunculi, Tansy, Monkshood, Dwale, HerbParis (Paris quadrifoliaL.))

  SUPPLIES OF CHEMICALS
    Fine chemicals, Intermediates

• Original Technology Development
• Scale Up
• Industrial Supplies

DNA diagnostics

 RT-PCR & microarrays

Bioanalysis

 HPLC-MS/MS, NMR

Schizophrenia, Parkinson,

 Alzheimer, Custom