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ANALYTICAL SERVICES

 ESSENCE LINE provides complete bionalytical services essential for monitoring human and animal biomarkers, biomarker discovery and drug development. In cooperation with academic institutes, we develop original analytical methods and apply them in practise using HPLC-MS/MS, NMR, RT-PCR and microarrays.

  •  Development of new Analytical and Screeening Methods applicable in clinical practise
  • Screening of new Potential Diagnostic Markers
  • Routine biomarker monitoring
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CNS PHARMACOGENETICS AND PHARMACOKINETICS

   

PHARMACOGENETICS USING MICROARRAYS

 Microdialysis in rodents using certified GMO animal facility

 Quantitative analysis of CNS biomarkers (LC-MS/MS, LC-MS QTOF, LC-UV, LC-ECD, NMR, qPCR, microarray)

 Routine HPLC-MS/MS analysis of neurotransmitters (dopamine, DOPAC, HVA, 3-MT, serotonin, 5-HIAA, norepinephrine, GABA, glutamate from microdialysis sample or brain tissue) and ROS biomarkers (leukotriens, prostaglandins, aldehydes)

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SUPPLIES OF CHEMICALS

   

Fine chemicals, intermediates, reagents, analytical standars

Original Technology Development

Scale Up

 Industrial Supplies

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ANIMAL CARE – SCREENING OF TOXINS

 

Elementary Analysis using XRF

Screening of Plant toxins using HPLC-MS and NMR

Complete toxin fingerprint

including the most common equine toxic plants (Ragweed, Yew, Ranunculi, Tansy, Monkshood, Dwale, HerbParis (Paris quadrifoliaL.)) 

MICROARRAY QUALITY INSPECTION​

Spot quality inspection using AFM

Homogeneity

Complete/partial spot absence

DNA aggregation and “donut-shaping”

morphological organization on nano-level

deposition of biomolecules (clustering, accretion, pooling)co-funded by EUREKA, European funding and support programme for SME research and development

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MEDICAL APPLICATIONS

 

Prenatal Diagnostics

Cancer Diagnostics

Metabolomics